The enhanced cancer nanovaccine by bidirectionally blocking CXCL12/CXCR4 axis to inhibit the recurrence and metastasis of triple-negative breast cancer
Abstract In situ cancer vaccine is a new method for cancer immunotherapy, however, the local immunosuppressive microenvironment of cancer tissue limits its immune response and therapeutic efficacy. The CXCL12/CXCR4 axis plays a key role in forming an immunosuppressive microenvironment. In this study...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2025-11-01
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| Colección: | Molecular Cancer |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s12943-025-02496-3 |
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