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B Quiet: Autoantigen-Specific Strategies to Silence Raucous B Lymphocytes and Halt Cross-Talk with T Cells in Type 1 Diabetes

Islet autoantibodies are the primary biomarkers used to predict type 1 diabetes (T1D) disease risk. They signal immune tolerance breach by islet autoantigen-specific B lymphocytes. T-B lymphocyte interactions that lead to expansion of pathogenic T cells underlie T1D development. Promising strategies...

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Principais autores: Jamie L. Felton, Holly Conway, Rachel H. Bonami
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-01-01
Serier:Biomedicines
Fag:
antibodies
autoantigen
autoimmunity
B cells
insulin
lymphocytes
Online adgang:https://www.mdpi.com/2227-9059/9/1/42
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