Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens

Abstract Several lines of evidence indirectly suggest that antigenic stimulation through the B‐cell receptor (BCR) supports chronic lymphocytic leukemia (CLL) development. In addition to self‐antigens, a number of microbial antigens have been proposed to contribute to the selection of the immunoglob...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Nereida Jiménez de Oya, Marco De Giovanni, Jessica Fioravanti, Rudolf Übelhart, Pietro Di Lucia, Amleto Fiocchi, Stefano Iacovelli, Dimitar G Efremov, Federico Caligaris‐Cappio, Hassan Jumaa, Paolo Ghia, Luca G Guidotti, Matteo Iannacone
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Springer Nature 2017-09-01
Sarja:	EMBO Molecular Medicine
Aiheet:	autoantigens B‐cell receptor chronic lymphocytic leukemia infection light chains
Linkit:	https://doi.org/10.15252/emmm.201707732
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