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Decline in estimated glomerular filtration rate following substitution of Nevirapine-based regimen with Tenofovir-based regimen in Indonesia

Abstract Background Indonesia started transitioning people living with HIV (PLHIV) from Nevirapine (NVP)-based antiretroviral therapy to tenofovir (TDF)-lamivudine-dolutegravir fixed-dose combination (TLD) in 2023. We aimed to evaluate changes in estimated glomerular filtration rate (eGFR) and predi...

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Principais autores: Evy Yunihastuti, Pringgodigdo Nugroho, Muhammad Yusuf, Salfia Dian Lastari, Fadlika Harinda, Tiara Kumala Putri, Meivina Ramadhani Pane, Metra Adi Pratama, Mira Yulianti, Alvina Widhani, Suzy Maria, Anshari Saifuddin Hasibuan, Maruhum Bonar Hasiholan Marbun, Sukamto Koesnoe, Teguh Harjono Karjadi
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-10-01
Series:BMC Infectious Diseases
Assuntos:
Dolutegravir
Drug substitution
Kidney function
Nevirapine
Tenofovir
ART
Acceso en liña:https://doi.org/10.1186/s12879-025-11710-y
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