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Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs.

The intestine is lined with isolated lymphoid follicles (ILFs) that facilitate sampling of luminal antigens to elicit immune responses. Technical challenges related to the scarcity and small sizes of ILFs and their follicle-associated epithelium (FAE) impeded the characterization of their spatial ge...

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Autori principali: Noam Cohen, Hassan Massalha, Shani Ben-Moshe, Adi Egozi, Milena Rozenberg, Keren Bahar Halpern, Shalev Itzkovitz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2021-10-01
Serie:PLoS Biology
Accesso online:https://doi.org/10.1371/journal.pbio.3001214
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