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Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs.

The intestine is lined with isolated lymphoid follicles (ILFs) that facilitate sampling of luminal antigens to elicit immune responses. Technical challenges related to the scarcity and small sizes of ILFs and their follicle-associated epithelium (FAE) impeded the characterization of their spatial ge...

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Библиографические подробности
Главные авторы: Noam Cohen, Hassan Massalha, Shani Ben-Moshe, Adi Egozi, Milena Rozenberg, Keren Bahar Halpern, Shalev Itzkovitz
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2021-10-01
Серии:PLoS Biology
Online-ссылка:https://doi.org/10.1371/journal.pbio.3001214
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