Synaptic and functional alterations in the development of mutant huntingtin expressing hiPSC‐derived neurons
Huntington’s disease (HD) is a monogenic disease that results in a combination of motor, psychiatric, and cognitive symptoms. It is caused by a CAG trinucleotide repeat expansion in the exon 1 of the huntingtin (HTT) gene, which results in the production of a mutant HTT protein (mHTT) with an extend...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2022-07-01
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| Seri Bilgileri: | Frontiers in Molecular Biosciences |
| Konular: | |
| Online Erişim: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.916019/full |
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