QR Code

Disrupting stroke-induced GAT-1-syntaxin1A interaction promotes functional recovery after stroke

Summary: Although stroke is a frequent cause of permanent disability, our ability to promote stroke recovery is limited. Here, we design a small-molecule stroke recovery promoting agent that works by dissociating γ-aminobutyric acid (GABA) transporter 1 (GAT-1) from syntaxin1A (Synt1A), a soluble N-...

Full description

Saved in:
Main Authors: Yu-Hui Lin, Feng Wu, Ting-You Li, Long Lin, Fan Gao, Li-Juan Zhu, Xiu-Mei Xu, Ming-Yu Chen, Ya-Lan Hou, Chang-Jing Zhang, Hai-Yin Wu, Lei Chang, Chun-Xia Luo, Ya-Juan Qin, Dong-Ya Zhu
Format: Artigo
Language:Inglês
Published: Elsevier 2024-11-01
Series:Cell Reports Medicine
Subjects:
stroke
GAT-1
syntaxin1A
network plasticity
functional recovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379124005366
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items