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Combination of eudragit EPO with poloxamers for improved solubility and dissolution of Zafirlukast: An evaluation of solid dispersion formulations

This study investigated the effect of solid dispersions (SD) on solubility and release of Zafirlukast (ZA) by physical mixture (PM), solvent evaporation (SE) and kneading method (KM) with Eudragit EPO (EPO) as binary component and Poloxamer 188 (P188) and Poloxamer 407 (P407) as ternary components....

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Principais autores: Zeeshan Masood, Muhammad Tayyab Ansari, Samina Afzal
Formato: Artigo
Idioma:Inglês
Publicado em: University of Karachi 2021-09-01
coleção:Pakistan Journal of Pharmaceutical Sciences
Acesso em linha:https://pjps.pk/single-article?id=cmrtzsqjv04138xguha0pr1lv
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