Microhomology directs diverse DNA break repair pathways and chromosomal translocations.
Chromosomal structural change triggers carcinogenesis and the formation of other genetic diseases. The breakpoint junctions of these rearrangements often contain small overlapping sequences called "microhomology," yet the genetic pathway(s) responsible have yet to be defined. We report a simple gene...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS Genetics |
| Acceso en liña: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003026&type=printable |
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