Cellular mRNA activates transcription elongation by displacing 7SK RNA.
The positive transcription elongation factor P-TEFb is a pivotal regulator of gene expression in higher cells. Originally identified in Drosophila, attention was drawn to human P-TEFb by the discovery of its role as an essential cofactor for HIV-1 transcription. It is recruited to HIV transcription...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2007-10-01
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| coleção: | PLoS ONE |
| Acesso em linha: | http://europepmc.org/articles/PMC1995758?pdf=render |
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