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The complex genetic architecture of Alzheimer's disease: novel insights and future directions

Summary: Background: Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disorder and the most common form of dementia. AD is highly heritable, with heritability estimates of ∼70% from twin studies. Progressively larger genome-wide association studies (GWAS) have continued to exp...

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Bibliografiset tiedot
Päätekijät: Shea J. Andrews, Alan E. Renton, Brian Fulton-Howard, Anna Podlesny-Drabiniok, Edoardo Marcora, Alison M. Goate
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2023-04-01
Sarja:EBioMedicine
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Linkit:http://www.sciencedirect.com/science/article/pii/S2352396423000762
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