Regulatory landscape enrichment analysis (RLEA): a computational toolkit for non-coding variant enrichment and cell type prioritization

Abstract Background As genomic studies continue to implicate non-coding sequences in disease, testing the roles of these variants requires insights into the cell type(s) in which they are likely to be mediating their effects. Prior methods for associating non-coding variants with cell types have inv...

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Ngā kaituhi matua:	Samuel Rosean, Eric A. Sosa, Dónal O’Shea, Srilakshmi M. Raj, Cathal Seoighe, John M. Greally
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2024-05-01
Rangatū:	BMC Bioinformatics
Ngā marau:	Cell-type prioritization Non-coding enrichment Chromatin architecture GWAS
Urunga tuihono:	https://doi.org/10.1186/s12859-024-05794-7
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!