Immunoproteasome Inhibition Positively Impacts the Gut‐Muscle Axis in Duchenne Muscular Dystrophy

ABSTRACT Background Duchenne Muscular Dystrophy (DMD) features immune‐muscle crosstalk, where muscle fibre degeneration enhances pro‐inflammatory macrophage infiltration, worsening inflammation and impairing regeneration. Methods We investigated the impact of immunoproteasome (IP) inhibition on the...

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Detalhes bibliográficos

Principais autores:	Andrea Farini, Francesco Strati, Monica Molinaro, Debora Mostosi, Sabrina Saccone, Luana Tripodi, Jacopo Troisi, Annamaria Landolfi, Chiara Amoroso, Barbara Cassani, Aitor Blanco‐Míguez, Emma Leonetti, Davide Bazzani, Mattia Bolzan, Francesco Fortunato, Flavio Caprioli, Federica Facciotti, Yvan Torrente
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-10-01
coleção:	Journal of Cachexia, Sarcopenia and Muscle
Assuntos:	Duchenne muscular dystrophy immunoproteasome macrophages muscle metabolism
Acesso em linha:	https://doi.org/10.1002/jcsm.70054
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