In Silico Prediction and Design of Uropathogenic <i>Escherichia coli</i> Alpha-Hemolysin Generate a Soluble and Hemolytic Recombinant Toxin

The secretion of α-hemolysin by uropathogenic <i>Escherichia coli</i> (UPEC) is commonly associated with the severity of urinary tract infections, which makes it a predictor of poor prognosis among patients. Accordingly, this toxin has become a target for diagnostic tests and therapeutic interventio...

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Principais autores:	Bruna De Lucca Caetano, Marta de Oliveira Domingos, Miriam Aparecida da Silva, Jessika Cristina Alves da Silva, Juliana Moutinho Polatto, Fabio Montoni, Leo Kei Iwai, Daniel Carvalho Pimenta, Hugo Vigerelli, Paulo Cesar Gomes Vieira, Rita de Cassia Ruiz, José Salvatore Patané, Roxane Maria Fontes Piazza
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-01-01
coleção:	Microorganisms
Assuntos:	bacterial toxins uropathogenic <i>Escherichia coli</i> alpha-hemolysin in silico prediction
Acesso em linha:	https://www.mdpi.com/2076-2607/10/1/172
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