Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome. The purpose of this study was to elucidate what virulence factors u...

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Opis bibliograficzny

Główni autorzy:	Isak Demirel, Alexander Persson, Annelie Brauner, Eva Särndahl, Robert Kruse, Katarina Persson
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2018-03-01
Seria:	Frontiers in Cellular and Infection Microbiology
Hasła przedmiotowe:	UPEC NLRP3 inflammasome IL-1β α-hemolysin type-1 fimbriae
Dostęp online:	http://journal.frontiersin.org/article/10.3389/fcimb.2018.00081/full
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