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Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies

Human exome sequencing has dramatically increased the rate of identification of disease-associated polymorphisms. However, examining the functional consequences of those variants has created an analytic bottleneck. Insulin-like signaling in Caenorhabditis elegans has long provided a model to assess...

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Bibliografische gegevens
Hoofdauteurs: David A. Bulger, Tetsunari Fukushige, Sijung Yun, Robert K. Semple, John A. Hanover, Michael W. Krause
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017-01-01
Reeks:G3: Genes, Genomes, Genetics
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Online toegang:http://g3journal.org/lookup/doi/10.1534/g3.116.037184
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