Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies

Human exome sequencing has dramatically increased the rate of identification of disease-associated polymorphisms. However, examining the functional consequences of those variants has created an analytic bottleneck. Insulin-like signaling in Caenorhabditis elegans has long provided a model to assess...

Descrición completa

Detalles Bibliográficos

Principais autores:	David A. Bulger, Tetsunari Fukushige, Sijung Yun, Robert K. Semple, John A. Hanover, Michael W. Krause
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 2017-01-01
Series:	G3: Genes, Genomes, Genetics
Assuntos:	DAF-2 INSR CRISPR Million Mutation Project dauer
Acceso en liña:	http://g3journal.org/lookup/doi/10.1534/g3.116.037184
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!