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HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia

The potential impact of lifestyle changes such as prolonged fasting on brain health still remains unclear. Neurodegenerative diseases often exhibit two key hallmarks: accumulation of misfolded proteins such as amyloid beta oligomers (AβO) and intracellular cholesterol accumulation. In this study, we...

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Principais autores: Joanne K. Agus, Oscar M. Muñoz Herrera, Christopher H. Rhodes, Jack Jingyuan Zheng, Chenghao Zhu, Maurice Wong, Xinyu Tang, Izumi Maezawa, Lee-Way Jin, Carlito B. Lebrilla, Danielle J. Harvey, Angela M. Zivkovic
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2025-08-01
叢編:Frontiers in Aging Neuroscience
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1629496/full
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