C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation

C3 glomerulopathy (C3G) is an ultra-rare complement-mediated kidney disease caused by to the deregulation of the alternative pathway (AP) of proximal complement. Consequently, all effector loops of the complement are active and can lead to pathologies, such as C3a- and C5a-mediated inflammation, C3b...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Karin Heidenreich, Deepti Goel, P. S. Priyamvada, Sagar Kulkarni, Vipul Chakurkar, Dinesh Khullar, Ravi Singh, Charan Bale, Peter F. Zipfel
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2024-10-01
سلاسل:	Frontiers in Nephrology
الموضوعات:	C3 glomerulopathy complement therapy complement inhibitors alternative pathway (AP)
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fneph.2024.1460146/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!