In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

T cell receptor (TCR)-redirected T cells target intracellular antigens such as Wilms’ tumor 1 (WT1), a tumor-associated antigen overexpressed in several malignancies, including acute myeloid leukemia (AML). For both chimeric antigen receptor (CAR)- and TCR-redirected T cells, several clinical studie...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sarah Bonte, Stijn de Munter, Lore Billiet, Glenn Goetgeluk, Joline Ingels, Hanne Jansen, Melissa Pille, Laurenz de Cock, Karin Weening, Tom Taghon, Georges Leclercq, Bart Vandekerckhove, Tessa Kerre
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2021-01-01
Цуврал:	OncoImmunology
Нөхцлүүд:	acute myeloid leukemia (aml) t cell immunotherapy common gamma chain cytokines hematopoietic stem cells op9-dl1
Онлайн хандалт:	http://dx.doi.org/10.1080/2162402X.2021.1954800
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!