Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Recent clinical studies indicate that adoptive T-cell therapy and especially chimeric antigen receptor (CAR) T-cell therapy is a very potent and potentially curative treatment for B-lineage hematologic malignancies. Currently, autologous peripheral blood T cells are used for adoptive T-cell therapy....

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Detalhes bibliográficos

Principais autores:	Yasmine Van Caeneghem, Stijn De Munter, Paola Tieppo, Glenn Goetgeluk, Karin Weening, Greet Verstichel, Sarah Bonte, Tom Taghon, Georges Leclercq, Tessa Kerre, Reno Debets, David Vermijlen, Hinrich Abken, Bart Vandekerckhove
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2017-03-01
Colecção:	OncoImmunology
Assuntos:	chimeric antigen receptor cord blood hematopoietic precursor cell hematopoietic stem cell immunotherapy t cell
Acesso em linha:	http://dx.doi.org/10.1080/2162402X.2017.1283460
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