Amelioration of experimental autoimmune encephalomyelitis by gemfibrozil in mice via PPARβ/δ: implications for multiple sclerosis

It is important to describe effective and non-toxic therapies for multiple sclerosis (MS), an autoimmune demyelinating disease. Experimental autoimmune encephalomyelitis (EAE) is an immune-mediated inflammatory disease that serves as a model for MS. Earlier we and others have shown that, gemfibrozil...

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Autores principales:	Susanta Mondal, Monica Sheinin, Suresh B. Rangasamy, Kalipada Pahan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-05-01
Colección:	Frontiers in Cellular Neuroscience
Materias:	gemfibrozil EAE MS blood–brain barrier neuroinflammation PPAR
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fncel.2024.1375531/full
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