Synthesis, Anticonvulsant, and Antinociceptive Activity of New 3-(2-Chlorophenyl)- and 3-(3-Chlorophenyl)-2,5-dioxo-pyrrolidin-1-yl-acetamides

The new series of 3-(2-chlorophenyl)- and 3-(3-chlorophenyl)-pyrrolidine-2,5-dione-acetamide derivatives as potential anticonvulsant and analgesic agents was synthesized. The compounds obtained were evaluated in the following acute models of epilepsy: maximal electroshock (MES), psychomotor (6 Hz, 3...

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Hlavní autoři:	Małgorzata Góra, Anna Czopek, Anna Rapacz, Anna Gębska, Katarzyna Wójcik-Pszczoła, Elżbieta Pękala, Krzysztof Kamiński
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-03-01
Edice:	Molecules
Témata:	anticonvulsant activity antinociceptive activity pyrrolidine-2,5-dione amides
On-line přístup:	https://www.mdpi.com/1420-3049/26/6/1564
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