4-(1-Methylamino)ethylidene-1,5-disubstituted pyrrolidine-2,3-diones: synthesis, anti-inflammatory effect and in silico approaches

Pyrrolidine-2,3-diones are important intermediates in the synthesis of numerous nitrogen-containing heterocycles which possess a broad spectrum of biological and pharmacological activities. In this article, we report the synthesis of 4-(1-methylamino)ethylidene-1,5-disubstituted pyrrolidine-2,3-dion...

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Principais autores:	Nguyen Tran Nguyen, Vo Viet Dai, Luc Van Meervelt, Do Thi Thao, Nguyen Minh Thong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Beilstein-Institut 2025-04-01
coleção:	Beilstein Journal of Organic Chemistry
Assuntos:	anti-inflammatory pyrrolidine-2,3-dione derivatives inos pyrrolidine-2,3-dione derivatives pyrrolidine-2,3-diones pyrrolidine-2,3-diones targeting reversible transimination reaction
Acesso em linha:	https://doi.org/10.3762/bjoc.21.65
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