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TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

Background Natural killer (NK) cells provide important immune protection from cancer and are a key requirement for particular immunotherapies. There is accumulating evidence that NK cells become dysfunctional during cancer. Overcoming NK cell exhaustion would be an important step to allow them to fu...

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書誌詳細
主要な著者: Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2021-02-01
シリーズ:Journal for ImmunoTherapy of Cancer
オンライン・アクセス:https://jitc.bmj.com/content/9/2/e002044.full
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