Inclusion Complexes of Melphalan with Gemini-Conjugated β-Cyclodextrin: Physicochemical Properties and Chemotherapeutic Efficacy in In-Vitro Tumor Models

β-cyclodextrin (βCD) has been widely explored as an excipient for pharmaceuticals and nutraceuticals as it forms stable host−guest inclusion complexes and enhances the solubility of poorly soluble active agents. To enhance intracellular drug delivery, βCD was chemically conjugat...

Descripción completa

Detalles Bibliográficos

Autores principales:	Waleed Mohammed-Saeid, Abdalla H Karoyo, Ronald E Verrall, Lee D Wilson, Ildiko Badea
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2019-08-01
Colección:	Pharmaceutics
Materias:	cationic gemini surfactant melphalan inclusion complex ROESY NMR spectroscopy 3D spheroid drug-resistant melanoma
Acceso en línea:	https://www.mdpi.com/1999-4923/11/9/427
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!