Inclusion Complexes of Melphalan with Gemini-Conjugated β-Cyclodextrin: Physicochemical Properties and Chemotherapeutic Efficacy in In-Vitro Tumor Models

β-cyclodextrin (βCD) has been widely explored as an excipient for pharmaceuticals and nutraceuticals as it forms stable host−guest inclusion complexes and enhances the solubility of poorly soluble active agents. To enhance intracellular drug delivery, βCD was chemically conjugat...

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Ngā kaituhi matua:	Waleed Mohammed-Saeid, Abdalla H Karoyo, Ronald E Verrall, Lee D Wilson, Ildiko Badea
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2019-08-01
Rangatū:	Pharmaceutics
Ngā marau:	cationic gemini surfactant melphalan inclusion complex ROESY NMR spectroscopy 3D spheroid drug-resistant melanoma
Urunga tuihono:	https://www.mdpi.com/1999-4923/11/9/427
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!