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Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution

Abstract Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling...

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Detaylı Bibliyografya
Asıl Yazarlar: Raphaël Mourad, Krzysztof Ginalski, Gaëlle Legube, Olivier Cuvier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2018-03-01
Seri Bilgileri:Genome Biology
Konular:
Online Erişim:http://link.springer.com/article/10.1186/s13059-018-1411-7
Etiketler: Etiketle
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