Improving fidaxomicin production through ARTP mutagenesis and fermentation optimization in Actinoplanes deccanensis
Fidaxomicin, a macrolide antibiotic, is widely used to treat Clostridioides difficile infection (CDI). It demonstrats significantly higher clinical efficacy than vancomycin and metronidazole. However, the large-scale industrial production of it remains a significant challenge because of the low ferm...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
KeAi Communications Co., Ltd.
2025-12-01
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| Colección: | Synthetic and Systems Biotechnology |
| Materias: | |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S2405805X25000870 |
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