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Improving fidaxomicin production through ARTP mutagenesis and fermentation optimization in Actinoplanes deccanensis

Fidaxomicin, a macrolide antibiotic, is widely used to treat Clostridioides difficile infection (CDI). It demonstrats significantly higher clinical efficacy than vancomycin and metronidazole. However, the large-scale industrial production of it remains a significant challenge because of the low ferm...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jing-Yi Ruan, Huang Xie, Yi-Lei Zheng, Qing-Wei Zhao, Xin-Ai Chen, Zhong-Yuan Lyu, Yong-Quan Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: KeAi Communications Co., Ltd. 2025-12-01
Rangatū:Synthetic and Systems Biotechnology
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2405805X25000870
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