Cationic antimicrobial peptide NRC-03 induces oral squamous cell carcinoma cell apoptosis via CypD-mPTP axis-mediated mitochondrial oxidative stress

Pleurocidin-family cationic antimicrobial peptide NRC-03 exhibits potent and selective cytotoxicity towards cancer cells. However, the anticancer effect of NRC-03 in oral squamous cell carcinoma (OSCC) and the molecular mechanism of NRC-03 induced cancer cell death is still unclear. This study focus...

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Detalhes bibliográficos

Principais autores:	Dan Hou, Fengjun Hu, Yixin Mao, Liang Yan, Yuhui Zhang, Zhichao Zheng, Antong Wu, Tymour Forouzanfar, Janak L. Pathak, Gang Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-08-01
coleção:	Redox Biology
Assuntos:	NRC-03 Oral squamous cell carcinoma Cyclophilin D Cell apoptosis Oxidative stress
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231722001276
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