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A Four-Step Purification Process for Gag VLPs: From Culture Supernatant to High-Purity Lyophilized Particles

Gag-based virus-like particles (VLPs) have high potential as scaffolds for the development of chimeric vaccines and delivery strategies. The production of purified preparations that can be preserved independently from cold chains is highly desirable to facilitate distribution and access worldwide. I...

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Principais autores: Irene González-Domínguez, Elianet Lorenzo, Alice Bernier, Laura Cervera, Francesc Gòdia, Amine Kamen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-10-01
Serier:Vaccines
Fag:
Gag VLPs
purification
clarification
chromatography
lyophilization
EVs
Online adgang:https://www.mdpi.com/2076-393X/9/10/1154
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