A Four-Step Purification Process for Gag VLPs: From Culture Supernatant to High-Purity Lyophilized Particles

Gag-based virus-like particles (VLPs) have high potential as scaffolds for the development of chimeric vaccines and delivery strategies. The production of purified preparations that can be preserved independently from cold chains is highly desirable to facilitate distribution and access worldwide. I...

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Главные авторы:	Irene González-Domínguez, Elianet Lorenzo, Alice Bernier, Laura Cervera, Francesc Gòdia, Amine Kamen
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-10-01
Серии:	Vaccines
Предметы:	Gag VLPs purification clarification chromatography lyophilization EVs
Online-ссылка:	https://www.mdpi.com/2076-393X/9/10/1154
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