Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn’s disease by promoting intestinal inflammation

Summary: Crohn’s disease (CD) is a kind of refractory intestinal inflammatory diseases. Pyroptosis was recently identified as a gasdermin-mediated proinflammatory cell death. However, it is unclear whether gasdermin-mediated pyroptosis participates in the pathogenesis of CD. Here, we show that the p...

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Үндсэн зохиолчид:	Gao Tan, Chongyang Huang, Jiaye Chen, Bingxia Chen, Fachao Zhi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2021-06-01
Цуврал:	Cell Reports
Нөхцлүүд:	Crohn's disease pyroptosis gasdermin E intestinal epithelial cell
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S221112472100632X
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!