Targeting QKI-7 in vivo restores endothelial cell function in diabetes
Abstract Vascular endothelial cell (EC) dysfunction plays a key role in diabetic complications. This study discovers significant upregulation of Quaking-7 (QKI-7) in iPS cell-derived ECs when exposed to hyperglycemia, and in human iPS-ECs from diabetic patients. QKI-7 is also highly expressed in hum...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2020-07-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-020-17468-y |
| Etykiety: |
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