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HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage.

The role of the E6 oncoprotein from high-risk members of the α human papillomavirus genus in anogenital cancer has been well established. However, far less is known about the E6 protein from the β human papillomavirus genus (β-HPVs). Some β-HPVs potentially play a role in non-melanoma skin cancer de...

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Hlavní autoři: Nicholas A Wallace, Kristin Robinson, Heather L Howie, Denise A Galloway
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS Pathogens
On-line přístup:https://doi.org/10.1371/journal.ppat.1002807
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