MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells

Background The recurrent immunoglobulin translocation, t(4;14)(p16;q32) occurs in 15% of multiple myeloma patients and is associated with poor prognosis, through an unknown mechanism. The t(4;14) up-regulates fibroblast growth factor receptor 3 (FGFR3) and multiple myeloma SET domain (MMSET) genes....

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Autori principali:	Jose L.R. Brito, Brian Walker, Matthew Jenner, Nicholas J. Dickens, Nicola J.M. Brown, Fiona M. Ross, Athanasia Avramidou, Julie A.E. Irving, David Gonzalez, Faith E. Davies, Gareth J. Morgan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Ferrata Storti Foundation 2009-01-01
Serie:	Haematologica
Accesso online:	https://haematologica.org/article/view/5148
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