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Cytoskeletal remodeling slows cross‐bridge cycling and ATP hydrolysis rates in airway smooth muscle

Abstract During isometric activation of airway smooth muscle (ASM), cross‐bridge cycling and ATP hydrolysis rates decline across time even though isometric force is sustained. Thus, tension cost (i.e., ATP hydrolysis rate per unit of force during activation) decreases with time. The “latch‐state” hy...

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Detalhes bibliográficos
Principais autores: Philippe Delmotte, Young‐soo Han, Gary C. Sieck
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-08-01
coleção:Physiological Reports
Assuntos:
Acesso em linha:https://doi.org/10.14814/phy2.14561
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