Clinicopathologic, genetic and immune cell infiltration analysis of colorectal signet ring cell carcinoma with comparison to conventional adenocarcinoma

Objective: We sought to characterize the genomic and immune landscape of signet ring cell carcinoma (SRCC), a rare and aggressive subtype of colorectal cancer (CRC). Methods: Tissue samples and clinicopathological data were retrospectively analyzed from 37 SRCC and 172 conventional adenocarcinomas (...

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Detalhes bibliográficos

Principais autores:	Yang An, Jiaolin Zhou, Lan Su, Lin Cong, Xinxin Mao, Bo Chen, Yuhua Gong, Yaping Xu, Han Chen, Chentong Wang, Guole Lin, Huanwen Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-02-01
coleção:	Journal of the National Cancer Center
Assuntos:	Signet ring cell carcinoma Genetic alterations Tumor-infiltrating lymphocytes Programmed cell death protein 1 Prognosis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2667005425001115
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