Case Report: Not all signet rings are of gastric origin: a case of lobular breast carcinoma metastatic to the stomach

BackgroundInvasive lobular carcinoma (ILC) is a distinct breast cancer subtype with a characteristic infiltrative growth pattern linked to loss of E-cadherin. GI metastases may clinically and histologically mimic primary GI malignancies, creating significant diagnostic pitfalls.Case presentationA 52...

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Hauptverfasser:	Amalia A. Sofianidi, Constantinos Papadimitris, Maria Papanikolaou, Eleftheria Lakiotaki, Penelope Korkolopoulou, Meletios-Athanasios Dimopoulos, Maria Kaparelou
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-06-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	breast cancer gastric metastasis GATA3 immunohistochemistry invasive lobular carcinoma signet ring
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1852381/full
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