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Differential Sex-Dependent Regulation of the Alveolar Macrophage miRNome of SP-A2 and co-ex (SP-A1/SP-A2) and Sex Differences Attenuation after 18 h of Ozone Exposure

Background: Human SP-A1 and SP-A2, encoded by <i>SFTPA1</i> and <i>SFTPA2</i>, and their genetic variants differentially impact alveolar macrophage (AM) functions and regulation, including the miRNome. We investigated whether miRNome differences previously observed between AM from SP-A2 and SP-A1/SP...

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Autores principales: Nithyananda Thorenoor, David S. Phelps, Joanna Floros
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2020-11-01
Colección:Antioxidants
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Acceso en línea:https://www.mdpi.com/2076-3921/9/12/1190
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