Zapotin mitigates breast cancer progression by targeting PKCε mediated glycolytic pathway regulation

Abstract Background The breast cancer recurrence and chemoresistance has increased over the years. A novel PKC, PKCε, may promote chemoresistance by causing hypoxia and cancer metabolic rewiring. A natural flavonoid, Zapotin, in colon cancer cells may modulate PKCε expression. Therefore, this study...

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Váldodahkkit:	Khushbukhat Khan, Maryam Anwar, Yasmin Badshah, Naeem Mahmood Ashraf, Arslan Hamid, Janeen H. Trembley, Maria Shabbir, Tayyaba Afsar, Fohad Mabood Husain, Dilawar Khan, Suhail Razak
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2025-04-01
Ráidu:	BMC Cancer
Fáttát:	Protein kinase C epsilon Zapotin MD simulations Breast cancer Metabolic rewiring
Liŋkkat:	https://doi.org/10.1186/s12885-025-14202-z
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