Zapotin mitigates breast cancer progression by targeting PKCε mediated glycolytic pathway regulation

Abstract Background The breast cancer recurrence and chemoresistance has increased over the years. A novel PKC, PKCε, may promote chemoresistance by causing hypoxia and cancer metabolic rewiring. A natural flavonoid, Zapotin, in colon cancer cells may modulate PKCε expression. Therefore, this study...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Khushbukhat Khan, Maryam Anwar, Yasmin Badshah, Naeem Mahmood Ashraf, Arslan Hamid, Janeen H. Trembley, Maria Shabbir, Tayyaba Afsar, Fohad Mabood Husain, Dilawar Khan, Suhail Razak
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-04-01
Serija:	BMC Cancer
Teme:	Protein kinase C epsilon Zapotin MD simulations Breast cancer Metabolic rewiring
Online dostop:	https://doi.org/10.1186/s12885-025-14202-z
Oznake:	Označite Brez oznak, prvi označite!