HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA
<p>Abstract</p> <p>Background</p> <p>The exact mechanism underlying HIV-associated neurocognitive disorders still remains largely unresolved. However, viral genes (for example <it>gp120 </it>and <it>tat</it>) and their effect on cytokine/chemokine expressions have been linked with neuroinflammation....
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2010-12-01
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| coleção: | Journal of Neuroinflammation |
| Acesso em linha: | http://www.jneuroinflammation.com/content/7/1/96 |
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