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DNA Vaccines Encoding HTNV GP-Derived Th Epitopes Benefited from a LAMP-Targeting Strategy and Established Cellular Immunoprotection

Vaccines has long been the focus of antiviral immunotherapy research. Viral epitopes are thought to be useful biomarkers for immunotherapy (both antibody-based and cellular). In this study, we designed a novel vaccine molecule, the Hantaan virus (HTNV) glycoprotein (GP) tandem Th epitope molecule (n...

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Autori principali: Dongbo Jiang, Junqi Zhang, Wenyang Shen, Yubo Sun, Zhenjie Wang, Jiawei Wang, Jinpeng Zhang, Guanwen Zhang, Gefei Zhang, Yueyue Wang, Sirui Cai, Jiaxing Zhang, Yongkai Wang, Ruibo Liu, Tianyuan Bai, Yuanjie Sun, Shuya Yang, Zilu Ma, Zhikui Li, Jijin Li, Chenjin Ma, Linfeng Cheng, Baozeng Sun, Kun Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-08-01
Serie:Vaccines
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Accesso online:https://www.mdpi.com/2076-393X/12/8/928
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