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DNA Vaccines Encoding HTNV GP-Derived Th Epitopes Benefited from a LAMP-Targeting Strategy and Established Cellular Immunoprotection

Vaccines has long been the focus of antiviral immunotherapy research. Viral epitopes are thought to be useful biomarkers for immunotherapy (both antibody-based and cellular). In this study, we designed a novel vaccine molecule, the Hantaan virus (HTNV) glycoprotein (GP) tandem Th epitope molecule (n...

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Principais autores: Dongbo Jiang, Junqi Zhang, Wenyang Shen, Yubo Sun, Zhenjie Wang, Jiawei Wang, Jinpeng Zhang, Guanwen Zhang, Gefei Zhang, Yueyue Wang, Sirui Cai, Jiaxing Zhang, Yongkai Wang, Ruibo Liu, Tianyuan Bai, Yuanjie Sun, Shuya Yang, Zilu Ma, Zhikui Li, Jijin Li, Chenjin Ma, Linfeng Cheng, Baozeng Sun, Kun Yang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-08-01
Colecção:Vaccines
Assuntos:
Hantaan virus (HTNV)
glycoprotein (GP)
Th epitopes
recombinant antigen
LAMP-targeting
Acesso em linha:https://www.mdpi.com/2076-393X/12/8/928
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