PYCR1 promotes liver cancer cell growth and metastasis by regulating IRS1 expression through lactylation modification

Abstract Background Liver cancer (LC) is among the deadliest cancers worldwide, with existing treatments showing limited efficacy. This study aimed to elucidate the role and underlying mechanisms of pyrroline‐5‐carboxylate reductase 1 (PYCR1) as a potential therapeutic target in LC. Methods Immunohi...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Haoyu Wang, Mu Xu, Tong Zhang, Jinkun Pan, Chaopu Li, Bei Pan, Linpeng Zhou, Yun Huang, Chenzi Gao, Mengping He, Yao Xue, Xuetao Ji, Xu Zhang, Ning Wang, Hongwen Zhou, Qian Wang, John Zhong Li
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Wiley 2024-10-01
Sarja:	Clinical and Translational Medicine
Aiheet:	h3k18 irs1 lactylation liver cancer pycr1
Linkit:	https://doi.org/10.1002/ctm2.70045
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