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Effect and mechanism of PYCR1 on biological function of hepatocellular carcinoma cells under hypoxia

Abstract Background Pyrrole-5-carboxylate reductase 1 (PYCR1) is a key enzyme involved in proline synthesis, which is closely related to the occurrence and development of liver cancer. In this study, we aimed to investigate the relationship and mechanism of PYCR1 on proline metabolism in hepatocellu...

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Autors principals: Jiayi Guo, Xinxin Jin, Junli Zhang, Yuming Zhang, Wenjuan Wu
Format: Artigo
Idioma:Inglês
Publicat: Springer 2025-06-01
Col·lecció:Discover Oncology
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Accés en línia:https://doi.org/10.1007/s12672-025-03028-7
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