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Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs

Many neurodegenerative diseases are characterized by deficiencies in neuronal axonal transport, a process in which cellular cargo is shuttled with the aid of molecular motors from the cell body to axonal termini and back along microtubules (MTs). Proper axonal transport is critical to the normal fun...

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Autori principali: Kurt R. Brunden, Virginia M-Y. Lee, Amos B. Smith, III, John Q. Trojanowski, Carlo Ballatore
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017-09-01
Serie:Neurobiology of Disease
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Accesso online:http://www.sciencedirect.com/science/article/pii/S0969996116303023
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